VANACIN-CP 500MG

About VANACIN-CP 500MG

Indications:

Used in the treatment of bacteremia, brain abscesses, acute leukemia, constipation and bowel evacuation, meningitis, endocarditis, chronic myeloid leukemia, colitis, peritoneal inflammation, endocarditis treatment, endocarditis prophylaxis, and relentless neutropenia in advanced HIV infection.

Indicators:

Mechanism of Action:

Vancomycin prevents integration of N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) peptide subunits from being unified into the peptidoglycan intercellular substance, which makes up the major functional constituent of Gram-positive cell walls. The sizable hydrophilic molecule is capable of making hydrogen bond interactions with the terminal D-alanyl-D-alanine portions of the NAM/NAG peptides. The binding of vancomycin to D-Ala-D-Ala precludes the consolidation of NAM/NAG peptide subunits into the peptidoglycan substance and changes bacterial cell membrane porosity as well as RNA synthesis.

Side Effects:

• Nephrotoxicity
• Excretory organ damage
• Uremia
• Hematuria
• Albuminuria
• Redness
• Fever
• Hypotension
• Flushing
• Urticaria skin rash
• Eosinophilia
• Red man syndrome

Drug Interaction:

Vancomycin is known to interact with other medications such as cyclosporin A, gentamicin, oxaliplatin, streptomycin, amphotericin B, metformin (HCl), tobramycin, and netilmicin (sulphate). Always consult with a physician for possible dose adjustments or alternative medication choices if required.

Specification:

• Usage: Hospital, Personal
• Dosage Form: Injection
• Packaging Type: Box
• Dose/Strength: 500 mg