Headache, depression, sleep problems. In high dose it may cause blindness, coma, and death. Stomach disturbances, loss of appetite, nausea, vomiting, constipation, diarrhea and mouth sore. Chest pain and irregular heart beat. Difficulty in breathing, pneumonia and severe lung toxicity. Hair loss, rash, hives and peeling skin. Fever, chills, cough and difficulty in swallowing.