|Seroquin - Seroquin is an antipsychotic (neuroleptic) drug. This medication exhibits a high affinity for serotonin 5HT2-receptors compared with dopamine D1- and D2-receptors in the brain. Also Seroquin has a high affinity for histamine and alpha1-receptors and a less pronounced - to the alpha2-receptors. This drug has no affinity for the m-cholinergic receptors.|
Seroquin in the dose effectively blocking dopamine D2-receptors causing only weak catalepsy. Seroquin selectively reduces the activity of mesolimbic dopamine neurons in A10-compared with A9-nigrostriatalnymi neurons involved in motor function. This medicine does not cause long raise prolactin levels.
In accordance with the results of positron emission tomography effect of Seroquin on serotonin 5HT2- and dopamine D2-receptors can be extended to 12 h.
Seroquin is used to treat schizophrenia and bipolar disorder (manic-depressive disorder). It helps to relieve symptoms common in schizophrenia and bipolar disorder, such as distorted thinking and emotional instability. Seroquin is also used together with other medicines to treat depression.
Treatment of schizophrenia, depressive episodes associated w/ bipolar disorder, acute manic episodes associated w/ bipolar I disorder, as either monotherapy or adjunct to lithium or divalproex. Maintenance treatment of bipolar I disorder as adjunct therapy to lithium or divalproex.
Seroquin fumarate, marketed by AstraZeneca as Seroquel or SeroquelXR and by Orion Pharma as Ketipinor, is an atypical antipsychotic used in the management of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression, and used off-label for a variety of other purposes, including insomnia and anxiety disorders.
|Active ingredients: Quetiapine|